This event is an official TOS Annual Meeting Preconference presented at ObesityWeek 2019. The event is free, and lunch is provided, but you must register in advance through ObesityWeek registration. Space is limited.

Obesity among children and young adults has escalated substantially over recent decades and now represents one of the major global health problems of the current era. Numerous mechanisms involved in the regulation of body fat and weight, when disturbed, can lead to diverse subtypes of obesity. Genetics, developmental influences (metabolic programming or epigenetic modification), and environmental factors all play important roles. Personalized approaches to the management of obesity in children and adolescents are key to improving quality of life and long-term successful outcomes. Using short lectures and illustrative case studies, this CME activity will describe emerging opportunities for precision medicine and advanced diagnostic testing to enhance obesity treatment in this population.

Learning Objectives
Upon successful completion of this activity, participants should be better able to:
• Describe the genetics associated with obesity from a global perspective.
• Characterize eating behavior phenotypes in relation to tailoring treatment selection.
• Assess the role of precision medicine in relation to advanced treatments for pediatric and adolescent obesity.
• Identify opportunities and barriers to optimizing pediatric and adolescent obesity management through case studies.

Target Audience
The intended audience for the activity is endocrinologists, family practice physicians, internists, obesity specialists and other health care professionals who manage pediatric and adolescent obesity.

This continuing medical education activity is provided by Vindico Medical Education. It is supported by an educational grant from Rhythm Pharmaceuticals, Inc.

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Vindico Medical Education designates this live activity for a maximum of 2.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

1:00pm Introduction and Pretest
Lee M Kaplan, MD PhD FTOS
1:05pm Monogenic Obesity and Implications for Therapy
Sonali Malhotra, MD
1:25pm Diagnosis and Management of Syndromic Obesity
Joan C Han, MD
1:45pm Polygenic Obesity and the Quest for Personalized Care
Lee M Kaplan, MD PhD FTOS
2:05pm Case Study Discussion
2:45pm Posttest
2:50pm Question and Answer