Background

Laparoscopic sleeve gastrectomy (LSG) is an effective treatment for obesity. Bone health related nutritional deficiencies have not been well studied in Asian bariatric populations. Our study aims to identify factors affecting baseline bone health in an Asian bariatric population and compare bone health at baseline and 1-year post-sleeve gastrectomy.

Methods

This is a retrospective analysis of 127 patients undergoing LSG at a tertiary institution in SGP between 2012 and 2018. Patient demographics, blood markers and bone densitometric measurements were compared pre- and 1 year post-operatively. Analysis was also done to identify factors that predict for 25-OH Vitamin D deficiency.

Results

There were 79 females and 48 males. The mean age was 44.5 (± 11.5) years and mean pre-op Body Mass Index (BMI) 41.6 (± 6.7) kg/m2. Pre-operatively, 25-OH Vitamin D deficiency (<10ng/mL) was seen in 36/127 (28.6%) and insufficiency (<30ng/ml) in 125/127 (98.4%). On univariate analysis, female gender, INDn race and class III obesity were significant predictors for baseline 25-OH Vitamin D deficiency. Table 1 shows a comparison of bone health markers.

Conclusions

Deficiency in all bone health markers improved significantly post-bariatric surgery. Vitamin D deficiency is highly prevalent in Asian bariatric population. Female gender, INDn race and class III obesity predict for vitamin D deficiency and thus, post-operative supplementation should be more stringent and compliance emphasized for them.