Laparoscopic roux-en-Y gastric bypass (LRYGB) patients are recommended to take multiple vitamin supplements daily. Transdermal multivitamin patches are being advertised for use in bariatric patients with no data to support its efficacy. The purpose of this study was to evaluate response to daily transdermal use of multivitamin patch after LRYGB and comparing them with a control group of similar patients who used oral supplements.


A retrospective review was carried out on patients who had LRYGB at a community hospital from February 2015 to February 2019. Patients who had completed preoperative and annual postoperative bariatric laboratory tests were included. They were divided into patch and pill (control) group.


21 patients were included in the patch and 27 in the pill group. Patients in each group used either patch or pills for at least 12 months. 81% patients in patch group and 44.4% in pill group had at least 1 deficiency at annual postoperative blood work (P = .0051). Vitamin D deficiency was seen in 80% patients in patch group versus 36% in pill group (P = .0032). A statistically significant lower postoperative serum concentrations of Vitamin D, B1, and B12 was seen in patch group. Folate and ferritin levels were also lower in the patch group.


Multivitamin patch users are more likely to have vitamin D deficiency and lower serum concentration of various vitamins and minerals. Future large studies are needed on the efficacy of multivitamin patches before they can be recommended to bariatric patient population.