Background

Obesity is a risk factor for the incidence of various diseases, such as non-alcoholic fatty liver disease. The objective of this study was to analyze the repercussions of BS on weight loss and on the hepatic profile of super-obese individuals at two different moments: preoperative and 6 months after BS. The study is characterized by a longitudinal study design with patients submitted to BS.

Methods

The sample consisted of 120 patients, 60% female, and 40% male, with a mean age of 41 years (+ 11.30), in which the weight and serum levels of alanine aminotransferase ( ALT) and aspartate aminotransferase (AST). Statistical analysis was performed by software R, using the Tukey test at 5% significance.

Results

In the preoperative evaluation, the mean weight of the patients was 116.55 kg (+ 20.91 Kg) and in the 6 months after BS was 77.32 kg (+ 13.43). Regarding the hepatic profile, there was no significant difference between the evaluated periods, and for ALT and AST, the mean values in the preoperative period were 30.27 U L-1 (+18.57 U L-1) and 26.74 (+ 11.64 U L-1), and after the BS was 26.88 U L-1 (+17.12 U L-1) and 25.7 U L-1 (11, 46 U L-1), respectively.

Conclusions

It can be observed that BS was efficient in weight reduction, however, it can not yet be said that this time or even this reduction in the patients' weight was enough to control liver changes.