Background

Olive(Orea europaa L.) leaf is a European and Mediterranean private medicine that has been used to treat malaria, high fever, etc. Recent studies have shown that olive leaf extracts are also effective in symptoms such as hypertension, arteriosclerosis, colon cancer, inflammation and diabetes. Recently, it has been reported that the study of Oleuropein among the polyphenols present in olive leaves is very active and effective in improving obesity11). However, obesity studies of olive leaf extracts on the human body are extremely rare

Methods

In this randomized, placebo-controlled, double-blind trial, 100 subjects were randomized. This Study assigned a total of 100 test subjects to 51 test groups and 49 control groups in two agencies. To evaluate this objective, visceral fat area and subcutaneous fat area were measured as the primary outcome. The test group takes 450 milligrams of olive leaf extract, and the control group takes placebo with the same weight and characteristics as the test food twice a day for 12 weeks, and twice a time.

Results

After 12weeks ingestion, OLD group showed a significant decrease in Visceral fat area(10.08±20.37cm2), and total abdominal fat area(18.62±32.85cm2) from baseline. And change of subcutaneous fat area(6.00±23.32cm2, p<0.05) and total abdominal fat area(18.62±32.85cm2, p<0.05) are significant changes compared to the control group. Total body fat mass and rate showed significant reduction compared to pre-consumption.

Conclusions

This study was conducted to examine the effects of Olive leaf extract ingestion on body fat reduction. Oluropein is known to effective in antioxidant, anti-inflammation. Antioxidant and anti-inflammatory effects of oleuropein are thought to affect body fat reduction as well.